Physical exercise and exercise intensity can influence laboratory test results resulting in misdiagnosis and unnecessary examinations if the physician is unaware of the patient’s training history. Acute exercise, including aerobic exercise and endurance training, can blast your body with uric acid, causing misreads for blood sugar and other body mass index testing. Let’s explore the effect of physical exercise on laboratory test results, LDL cholesterol, glucose concentration, free fatty acids, and more with Ehline Law and our injury attorneys.
The following are findings from studies exploring the relationship between physical exercise, cardiovascular risk, and some plasma volume and blood volume indicators on lab tests.
Acute physical exercise can have a significant impact on the red blood cell count due to hemoconcentration, which increases the following concentrations between 10% and 30%:
The percentage change depends on the intensity and duration of the exercise. Short physical activity, such as sprinting, elevates all three indicators, returning to the normal range within 30 minutes.
Depending on the intensity of the physical exercise, there is a significant change in leukocytosis. For example, in intense exercise training, leukocytosis can reach twice the normal levels, while it immediately jumps up by between 50% and 100% after an endurance exercise. Not many studies examine the white blood cell count and alkaline phosphatase in endurance athletes (female and male athletes.)
After a marathon run or strenuous exercise, marathon runners showed a significantly shorter euglobulin lysis time while having a significantly elevated degradation product B and D-dimer concentration, even with increased fluid intake and expected electrolyte balance. It also increases the tissue plasminogen activator almost 30 times before returning to normal after three hours.
Study shows that exercise training results in the following statistical significance:
Since coagulation remains longer than fibrinolysis, the recovery phase can cause thromboembolic events in some patients. Investigations reveal that physical exertion does not consistently affect the fibrinolytic system, but it does affect the fibrinolytic activity. Independent analysis of fibrinogen can be a great indicator of cardiovascular disease and other inflammatory markers.
The 1986 study published in the Journal of Applied Physiology that studies the effects of a marathon race on blood platelet activation and thrombin activity revealed the following:
A study by Eichner ER in 1986, published in The Physician and Sportsmedicine journal, revealed that athletes could develop anemia. However, evaluating the red blood cell count is rather complex, and the physician must consider changes in complete blood cell count as well as physiological adaptation.
Several studies conducted in the past showed the impact of physical activity on other blood compounds and platelet counts, including sodium, potassium, magnesium, and red blood cells.
Traces of blood or protein is often detected in urine after 24 to 48 hours of exercise due to repetitive muscle breakdown. Exercise or endurance training can also increase the muscle enzyme creatine kinase in the body, but these often return to normal levels after a week of recovery and rehydration.
Sweating from exercise or intaking too much fluids can affect hydration levels in the body, resulting in high or low levels of red and white blood cells and creatine concentrations, both being a serious concern.
When exercising, glucose levels in the blood can drop significantly to counteract the side effects of muscle contraction. During this time, the liver excretes more glucose to the muscles causing an increase in blood glucose levels and decreasing blood insulin. The blood test results may seem worrisome if they lead to medical conditions.
The doctors use results from blood tests to help diagnose patients. However, because there can be changes in blood test results due to exercise, physicians also use other indicators, such as blood pressure, pulse, and symptoms, for accurate diagnosis.
Doctors must stay updated on all the latest studies and consider all factors before diagnosing a patient, as misdiagnosis can further affect a patient’s health. If you suffered injuries or deteriorating health due to misdiagnosis, contact us at (833) LETS-SUE for a free consultation, as you may be eligible for compensation.
Michael is a managing partner at the nationwide Ehline Law Firm, Personal Injury Attorneys, APLC. He’s an inactive Marine and became a lawyer in the California State Bar Law Office Study Program, later receiving his J.D. from UWLA School of Law. Michael has won some of the world’s largest motorcycle accident settlements.